Cigarette smoke induces angiogenic activation in the cancer field through dysregulation of an endothelial microRNA

Cigarette smoke induces angiogenic activation in the cancer field through dysregulation of an endothelial microRNA

Abstract Cigarette smoke (CS) creates a “cancer field” in the lung that promotes malignant transformation. The molecular changes within this field are not fully characterized. We examined the significance of microRNA-1 (miR-1) downregulation as one of these changes. We found that tumor miR-1 levels...

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Main Authors: Asawari Korde, Anuradha Ramaswamy, Seth Anderson, Lei Jin, Jian-ge Zhang, Buqu Hu, Walter V. Velasco, Lixia Diao, Jing Wang, Margaret A. Pisani, Maor Sauler, Daniel J. Boffa, Jonathan T. Puchalski, Xiting Yan, Seyed Javad Moghaddam, Shervin S. Takyar
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-07710-y
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https://doi.org/10.1038/s42003-025-07710-y

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