Targeting glycolysis for neuroprotection in early LPS-induced neuroinflammation

Targeting glycolysis for neuroprotection in early LPS-induced neuroinflammation

Neuroinflammation is a pathophysiological feature of numerous neurological and psychiatric disorders. The immune response in the central nervous system, driven by microglia and astrocytes, leads to metabolic reprogramming towards aerobic glycolysis, a phenomenon known as the Warburg effect. The cont...

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Main Authors: Adriana Fernanda K. Vizuete, Fernanda Fróes, Marina Seady, Aline Castro Caurio, Osmar Vieira Ramires Junior, Ana Karla Oliveira Leite, Clarissa Penha Farias, Angela T.S. Wyse, Carlos-Alberto Gonçalves
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Brain, Behavior, & Immunity - Health
Subjects:
Neuroinflammation
LPS
Aerobic glycolysis
3PO
MCC950
Online Access:http://www.sciencedirect.com/science/article/pii/S2666354624001790
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