A Novel CTC-Binding Probe: Enzymatic vs. Shear Stress-Based Detachment Approaches

A Novel CTC-Binding Probe: Enzymatic vs. Shear Stress-Based Detachment Approaches

<b>Background/Objectives</b>: Liquid biopsy is a minimally invasive alternative to tissue biopsy and is used to obtain information about a disease from a blood sample or other body fluids. In the context of cancer, circulating tumor cells (CTC) can be used as biomarkers to determine the...

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Bibliographic Details
Main Authors: Sophia Krakowski, Sara Campos, Henri Wolff, Gabi Bondzio, Felix Hehnen, Michael Lommel, Ulrich Kertzscher, Paul Friedrich Geus
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Diagnostics
Subjects:
circulating tumor cells (CTC)
TrypLE™
BMProbe™
cell detachment
wall shear stress
Online Access:https://www.mdpi.com/2075-4418/15/15/1876
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