Histopathological and immunohistochemical findings in different tissues of goats infected with small ruminant lentivirus
<b>Aim:</b> Small ruminant lentivirus infections has chronic and incurable character that might simultaneously and immunopathogenically affect several major target organs, causing pathological and clinical mastitis, maedi, visna, and arthritis in sheep and goats. This study aimed to reve...
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Selcuk University Press
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| Series: | Eurasian Journal of Veterinary Sciences |
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| Online Access: | http://eurasianjvetsci.org/pdf.php3?id=1424 |
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| author | Ozgur Kanat Veysel Soydal Ataseven Ilke Evrim Secinti Veli Incecik Firat Dogan |
| author_facet | Ozgur Kanat Veysel Soydal Ataseven Ilke Evrim Secinti Veli Incecik Firat Dogan |
| author_sort | Ozgur Kanat |
| collection | DOAJ |
| description | <b>Aim:</b> Small ruminant lentivirus infections has chronic and incurable character
that might simultaneously and immunopathogenically affect several major
target organs, causing pathological and clinical mastitis, maedi, visna, and
arthritis in sheep and goats. This study aimed to reveal the lesions and
their cellular distribution in different tissues of histopathologically and
immunohistochemically infected goats.<p>
<b>Materials and Methods:</b> A total of six goats, known as seropositive, and
one aborted fetus, were used for the study. Histopathologic findings and
immunohistochemical cellular distributions were determined.<p>
<b>Results: </b>Histopathologically, bronchopneumonia and chronic interstitial
pneumonia, enteritis, hyaline droplets and hyaline cylinders, hydropic
degeneration and necrosis of proximal and distal tubular epithelium in the
kidneys, congestion and decrease of lymphoid cells in the spleen, congestion,
hyaline degeneration and necrosis in the heart, and hydropic degeneration,
necrosis and hepatitis in the liver were observed. Immunohistochemically,
positive staining was observed in the epithelium of the bronchi and
bronchioles, alveolar macrophages and lymphocytes in the lung, lymphocytes
and macrophages in the spleen, crypt, and villous epitelium, lymphocytes
and macrophages in the intestine, and Kupffer cells and lymphocytes in the
liver. In contrast, no positivity was observed in the kidneys and heart.<p>
<b>Conclusion: </b>It is anticipated that the data obtained on small ruminant
lentivirus infections will have an important place in goat breeding and will
be important for new studies and control programs that may be developed. |
| format | Article |
| id | doaj-art-f8d32950afa84d24a1af4c939f72c108 |
| institution | Kabale University |
| issn | 1309-6958 2146-1953 |
| language | English |
| publisher | Selcuk University Press |
| record_format | Article |
| series | Eurasian Journal of Veterinary Sciences |
| spelling | doaj-art-f8d32950afa84d24a1af4c939f72c1082025-01-03T01:36:12ZengSelcuk University PressEurasian Journal of Veterinary Sciences1309-69582146-195339292991424Histopathological and immunohistochemical findings in different tissues of goats infected with small ruminant lentivirusOzgur Kanat0Veysel Soydal Ataseven1Ilke Evrim Secinti2Veli Incecik3Firat Dogan4Necmettin Erbakan University Faculty of Veterinary Medicine, Department of Pathology, Konya, TürkiyeDepartment of Virology, Faculty of Veterinary Medicine, Hatay Mustafa Kemal University, Hatay, Türkiye,Department of Pathology, Faculty of Medicine, Hatay Mustafa Kemal University, Hatay, TürkiyeEfendioglu Slaughterhouse, Kahramanmaras, TürkiyeDepartment of Virology, Faculty of Veterinary Medicine, Hatay Mustafa Kemal University, Hatay, Türkiye,<b>Aim:</b> Small ruminant lentivirus infections has chronic and incurable character that might simultaneously and immunopathogenically affect several major target organs, causing pathological and clinical mastitis, maedi, visna, and arthritis in sheep and goats. This study aimed to reveal the lesions and their cellular distribution in different tissues of histopathologically and immunohistochemically infected goats.<p> <b>Materials and Methods:</b> A total of six goats, known as seropositive, and one aborted fetus, were used for the study. Histopathologic findings and immunohistochemical cellular distributions were determined.<p> <b>Results: </b>Histopathologically, bronchopneumonia and chronic interstitial pneumonia, enteritis, hyaline droplets and hyaline cylinders, hydropic degeneration and necrosis of proximal and distal tubular epithelium in the kidneys, congestion and decrease of lymphoid cells in the spleen, congestion, hyaline degeneration and necrosis in the heart, and hydropic degeneration, necrosis and hepatitis in the liver were observed. Immunohistochemically, positive staining was observed in the epithelium of the bronchi and bronchioles, alveolar macrophages and lymphocytes in the lung, lymphocytes and macrophages in the spleen, crypt, and villous epitelium, lymphocytes and macrophages in the intestine, and Kupffer cells and lymphocytes in the liver. In contrast, no positivity was observed in the kidneys and heart.<p> <b>Conclusion: </b>It is anticipated that the data obtained on small ruminant lentivirus infections will have an important place in goat breeding and will be important for new studies and control programs that may be developed.http://eurasianjvetsci.org/pdf.php3?id=1424goathistopathologyimmunohistochemistrysmall ruminant lentivirus |
| spellingShingle | Ozgur Kanat Veysel Soydal Ataseven Ilke Evrim Secinti Veli Incecik Firat Dogan Histopathological and immunohistochemical findings in different tissues of goats infected with small ruminant lentivirus Eurasian Journal of Veterinary Sciences goat histopathology immunohistochemistry small ruminant lentivirus |
| title | Histopathological and immunohistochemical findings in different tissues of goats infected with small ruminant lentivirus |
| title_full | Histopathological and immunohistochemical findings in different tissues of goats infected with small ruminant lentivirus |
| title_fullStr | Histopathological and immunohistochemical findings in different tissues of goats infected with small ruminant lentivirus |
| title_full_unstemmed | Histopathological and immunohistochemical findings in different tissues of goats infected with small ruminant lentivirus |
| title_short | Histopathological and immunohistochemical findings in different tissues of goats infected with small ruminant lentivirus |
| title_sort | histopathological and immunohistochemical findings in different tissues of goats infected with small ruminant lentivirus |
| topic | goat histopathology immunohistochemistry small ruminant lentivirus |
| url | http://eurasianjvetsci.org/pdf.php3?id=1424 |
| work_keys_str_mv | AT ozgurkanat histopathologicalandimmunohistochemicalfindingsindifferenttissuesofgoatsinfectedwithsmallruminantlentivirus AT veyselsoydalataseven histopathologicalandimmunohistochemicalfindingsindifferenttissuesofgoatsinfectedwithsmallruminantlentivirus AT ilkeevrimsecinti histopathologicalandimmunohistochemicalfindingsindifferenttissuesofgoatsinfectedwithsmallruminantlentivirus AT veliincecik histopathologicalandimmunohistochemicalfindingsindifferenttissuesofgoatsinfectedwithsmallruminantlentivirus AT firatdogan histopathologicalandimmunohistochemicalfindingsindifferenttissuesofgoatsinfectedwithsmallruminantlentivirus |