Endogenous tyrosinase-catalyzed therapeutics

Abstract Tyrosinase (TYR) catalyzes the two initial steps of melanin synthesis from tyrosine in various organisms. However, overproduction, accumulation, and abnormal reduction of melanin can lead to severe diseases, particularly skin diseases, which makes tyrosinase a significant endogenous target...

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Bibliographic Details
Main Authors: Yawen You, Zhaochen Guo, Yixin Wang, Sichen Yuan, Quanyin Hu
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61799-7
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