New insight into the role of the pathway NLRP1 and NLRP3 inflammasomes and IL-33 in ultraviolet-induced cutaneous carcinogenesis

New insight into the role of the pathway NLRP1 and NLRP3 inflammasomes and IL-33 in ultraviolet-induced cutaneous carcinogenesis

IntroductionInflammasomes NLRP1 (NLR family pyrin domain containing 1) and NLRP3 are pivotal regulators of the innate immune response, activated by a spectrum of endogenous and exogenous stressors, including ultraviolet radiation (UVR). The precise molecular mechanisms underlying the activation of t...

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Main Authors: Aleksandra Lesiak, Karolina Wodz, Justyna Ceryn, Dorota Sobolewska-Sztychny, Igor Bednarski, Janusz Piekarski, Marta Pabianek, Dariusz Nejc, Izabela Dróżdż, Joanna Narbutt, Marcin Noweta, Magdalena Ciążyńska
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Medicine
Subjects:
inflammasome
NLRP1
NLRP3
IL-33
cutaneous carcinogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2024.1483208/full
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