Population pharmacokinetic modeling of paired plasma–breast milk lamivudine data for estimation of infant exposure in breastfeeding mother–infant pairs

Population pharmacokinetic modeling of paired plasma–breast milk lamivudine data for estimation of infant exposure in breastfeeding mother–infant pairs

Abstract Around 1.2 million women living with HIV give birth annually, majority of whom will breastfeed their infants while receiving antiretroviral therapy (ART). Lamivudine, a component of first‐line ART regimens crosses from maternal plasma to breast milk, with measurable concentrations in some b...

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Main Authors: Francis Williams Ojara, Aida N. Kawuma, Shadia Nakalema, Isabella Kyohairwe, Ritah Nakijoba, Mohammed Lamorde, Henry Pertinez, Saye Khoo, Catriona Waitt
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:CPT: Pharmacometrics & Systems Pharmacology
Online Access:https://doi.org/10.1002/psp4.13274
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https://doi.org/10.1002/psp4.13274

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