RNF13 protects neurons against ischemia-reperfusion injury via stabilizing p62-mediated Nrf2/HO-1 signaling pathway

RNF13 protects neurons against ischemia-reperfusion injury via stabilizing p62-mediated Nrf2/HO-1 signaling pathway

Abstract Background Cerebral ischemia/reperfusion injury (CIRI), a common, universal clinical problem that costs a large proportion of the economic and disease burden. Identifying the key regulators of cerebral I/R injury could provide potential strategies for clinically improving the prognosis of s...

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Main Authors: Qiangping Wang, Shuang Li, Wenjie Wu, Wenke Zhou, Kaixuan Yan, Zhen Liu, Lanlan Yan, Baoping Zheng, Fangcheng Zhang, Xiaobing Jiang, Youfan Ye, Haijun Wang
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Cell Communication and Signaling
Subjects:
RNF13
Ischemia reperfusion (I/R) injury
Stroke
p62/Nrf2/HO-1
Pathway
Online Access:https://doi.org/10.1186/s12964-024-01905-2
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https://doi.org/10.1186/s12964-024-01905-2

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