Biochemical detection of pediatric eosinophilic esophagitis using high wavenumber Raman endoscopy and stimulated Raman microscopy

Biochemical detection of pediatric eosinophilic esophagitis using high wavenumber Raman endoscopy and stimulated Raman microscopy

Abstract Eosinophilic esophagitis (EoE) is an immunoinflammatory condition of the esophagus characterized by an intense eosinophilic inflammation. Given its chronic and progressive course, EoE can lead to esophageal remodeling and dysphagia. Current diagnostic methods require repeated endoscopy to r...

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Main Authors: Ezekiel J. Haugen, Andrea K. Locke, Lily H. Dao, Alec B. Walter, Pratheepa K. Rasiah, Justin S. Baba, Matthew A. Buendia, Hernán Correa, Girish Hiremath, Anita Mahadevan-Jansen
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Raman spectroscopy
Stimulated Raman microscopy
Eosinophilic esophagitis
Biomolecules
Clinical translation
Online Access:https://doi.org/10.1038/s41598-025-05591-z
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https://doi.org/10.1038/s41598-025-05591-z

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