Novel targeted therapies in chronic myeloid leukemia
Chronic myeloid leukemia (CML) is the chronic proliferation of myeloid-lineage cells in hematopoietic stem cells driven by the BCR-ABL1 fusion oncoprotein. The development of tyrosine kinase inhibitors (TKIs) has revolutionized CML treatment; however, resistance and intolerance to these drugs remain...
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Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-12-01
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Series: | Pharmaceutical Science Advances |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2773216924000187 |
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