AID‐expressing epithelium is protected from oncogenic transformation by an NKG2D surveillance pathway
Abstract Activation‐induced deaminase (AID) initiates secondary antibody diversification in germinal center B cells, giving rise to higher affinity antibodies through somatic hypermutation (SHM) or to isotype‐switched antibodies through class switch recombination (CSR). SHM and CSR are triggered by...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2015-08-01
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| Series: | EMBO Molecular Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.15252/emmm.201505348 |
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