Pyroptosis, a double-edged sword during pathogen infection: a review

Abstract Pyroptosis, a distinctive form of programmed cell death (PCD) characterized by its inflammatory nature, is triggered by the activation of pore-forming proteins known as gasdermins (GSDMs). This process is marked by progressive expansion of a pore within the cell, ultimately leading to cellu...

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Bibliographic Details
Main Authors: Yuanhang Zhang, Dengshuai Zhao, Tianyu Wang, Ping Li, Dixi Yu, Han Gao, Mengmeng Zhao, Limei Qin, Keshan Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2025-07-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-025-02579-6
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