Roles of the developmental regulator unc-62/Homothorax in limiting longevity in Caenorhabditis elegans.
The normal aging process is associated with stereotyped changes in gene expression, but the regulators responsible for these age-dependent changes are poorly understood. Using a novel genomics approach, we identified HOX co-factor unc-62 (Homothorax) as a developmental regulator that binds proximal...
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Main Authors: | Eric L Van Nostrand, Adolfo Sánchez-Blanco, Beijing Wu, Andy Nguyen, Stuart K Kim |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS Genetics |
Online Access: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1003325&type=printable |
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