Advancements in TDP-43 research: Towards biomarkers and therapeutic targets for amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) remains a devastating neurodegenerative disease characterized by progressive motor neuron degeneration, leading to paralysis and premature death. Despite advances in understanding its pathology, ALS diagnosis and treatment remain primarily symptomatic, lacking dis...

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Bibliographic Details
Main Authors: Yuhan Wu, Jie Wang, Qianhua Zhao
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Aging and Health Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667032124000362
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