Selective TCRαβ+ and CD45RA+ T-cell depletion of hematopoietic stem cell graft: An analysis on factors that affect depletion performance

Selective depletion of TCRαβ+ and CD45RA+ subsets of apheresed hematopoietic progenitor cells, HPC(A), enables haploidentical hematopoietic stem cell transplant (haplo-HSCT) by circumventing risks of graft-versus-host disease. Here, we analyze our institution’s large series of ex vivo T-cell depleti...

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Bibliographic Details
Main Authors: Chieh Hwee Ang, Gina Gan, Ren How Ho, Kee Khiang Heng, Yeh Ching Linn
Format: Article
Language:English
Published: SAGE Publishing 2025-05-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/09636897251336965
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