Imaging sensory transmission and neuronal plasticity in primary sensory neurons with a positively tuned voltage indicator

Abstract Primary sensory neurons convert external stimuli into electrical signals, yet how heterogeneous neurons encode distinct sensations remains unclear. In vivo dorsal root ganglia (DRG) imaging with genetically-encoded Ca2+ indicators (GECIs) enables mapping of neuronal activity from over 1800...

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Bibliographic Details
Main Authors: Yan Zhang, John Shannonhouse, Ruben Gomez, Hyeonwi Son, Hirotake Ishida, Stephen Evans, Mariya Chavarha, Dongqing Shi, Guofeng Zhang, Michael Z. Lin, Yu Shin Kim
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61774-2
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