An experimental study on the effect of topicafly used atropine on tear production of dogs

The study was undertaken to determine the effects of short and long-term local administration ol at-ropine.which is frequently used for treatment of various eye diseases and preanaesthetic medication,on tear production.Eight healty mongrel dogs were used in the study To observe the short-term effect...

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Main Authors: Celal İzci, Sırrı Avki, Fahrettin Alkan
Format: Article
Language:English
Published: Selcuk University Press
Series:Eurasian Journal of Veterinary Sciences
Subjects:
Online Access:http://eurasianjvetsci.org/pdf.php3?id=665
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author Celal İzci
Sırrı Avki
Fahrettin Alkan
author_facet Celal İzci
Sırrı Avki
Fahrettin Alkan
author_sort Celal İzci
collection DOAJ
description The study was undertaken to determine the effects of short and long-term local administration ol at-ropine.which is frequently used for treatment of various eye diseases and preanaesthetic medication,on tear production.Eight healty mongrel dogs were used in the study To observe the short-term effects of local atropine administration, the dogs have taken one drop of t% atropine sulphate solution on the right eye after obtaining the normal lacrimal secrete amount of right and left eyes by Schirmer I tear test and the tear values of each eyes were measured at 15,30,60,90,120,240,360 and 480 minutes intervals by same method e To confirme the long-term effects of atropine,the same animals have taken one drop of atropine solution or the right eye every morning and Schirmer I tear test values of each eyes were measured for seven days. After the completion of drug administration,measurements of each eyes were continued two times per day for seven days. The short-term use of atropine was resulted in a decrease of right eye tear production on an average of 34% after 90 minutes and approached to normal vaiues after 240 minutes meanwhile the left one had a decrease on an average of 22.7% after 60 minutes and reached to beginning values after 90 minutes.ln the long-term use of atropine, an increase of tear production was confirmed and found conspicuous statistically in the course of seven days after the completion of drug administration.
format Article
id doaj-art-f674923422c4417daa19f1879ca8d84d
institution Kabale University
issn 1309-6958
2146-1953
language English
publisher Selcuk University Press
record_format Article
series Eurasian Journal of Veterinary Sciences
spelling doaj-art-f674923422c4417daa19f1879ca8d84d2025-01-03T01:36:52ZengSelcuk University PressEurasian Journal of Veterinary Sciences1309-69582146-19531112531665An experimental study on the effect of topicafly used atropine on tear production of dogsCelal İzciSırrı AvkiFahrettin AlkanThe study was undertaken to determine the effects of short and long-term local administration ol at-ropine.which is frequently used for treatment of various eye diseases and preanaesthetic medication,on tear production.Eight healty mongrel dogs were used in the study To observe the short-term effects of local atropine administration, the dogs have taken one drop of t% atropine sulphate solution on the right eye after obtaining the normal lacrimal secrete amount of right and left eyes by Schirmer I tear test and the tear values of each eyes were measured at 15,30,60,90,120,240,360 and 480 minutes intervals by same method e To confirme the long-term effects of atropine,the same animals have taken one drop of atropine solution or the right eye every morning and Schirmer I tear test values of each eyes were measured for seven days. After the completion of drug administration,measurements of each eyes were continued two times per day for seven days. The short-term use of atropine was resulted in a decrease of right eye tear production on an average of 34% after 90 minutes and approached to normal vaiues after 240 minutes meanwhile the left one had a decrease on an average of 22.7% after 60 minutes and reached to beginning values after 90 minutes.ln the long-term use of atropine, an increase of tear production was confirmed and found conspicuous statistically in the course of seven days after the completion of drug administration.http://eurasianjvetsci.org/pdf.php3?id=665dogtear productionatropine sulphate
spellingShingle Celal İzci
Sırrı Avki
Fahrettin Alkan
An experimental study on the effect of topicafly used atropine on tear production of dogs
Eurasian Journal of Veterinary Sciences
dog
tear production
atropine sulphate
title An experimental study on the effect of topicafly used atropine on tear production of dogs
title_full An experimental study on the effect of topicafly used atropine on tear production of dogs
title_fullStr An experimental study on the effect of topicafly used atropine on tear production of dogs
title_full_unstemmed An experimental study on the effect of topicafly used atropine on tear production of dogs
title_short An experimental study on the effect of topicafly used atropine on tear production of dogs
title_sort experimental study on the effect of topicafly used atropine on tear production of dogs
topic dog
tear production
atropine sulphate
url http://eurasianjvetsci.org/pdf.php3?id=665
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AT sırrıavki anexperimentalstudyontheeffectoftopicaflyusedatropineontearproductionofdogs
AT fahrettinalkan anexperimentalstudyontheeffectoftopicaflyusedatropineontearproductionofdogs
AT celalizci experimentalstudyontheeffectoftopicaflyusedatropineontearproductionofdogs
AT sırrıavki experimentalstudyontheeffectoftopicaflyusedatropineontearproductionofdogs
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