Elderly individuals exhibit dysregulated monocyte responses to viral immune complexes compared to adults and children

Elderly individuals exhibit dysregulated monocyte responses to viral immune complexes compared to adults and children

Abstract The severity of certain viral infectious diseases varies across the age; we hypothesize that these variations could be related to the variation of immune responses to viral immune complexes (ICs) among the age. This study aimed to investigate monocyte activation in response to ICs in childr...

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Bibliographic Details
Main Authors: Léa Domitien Payet, Anthony Coléon, Anne Sophie Bedin, Lucas Auguste, Maël Morvan Duroyon, Caroline Mollevi, Hubert Blain, Franck Mennechet, Éric Jeziorski, Édouard Tuaillon
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Immune complexes
Monocytes activation
Immunosenescence
Inflammaging
Online Access:https://doi.org/10.1038/s41598-025-13883-7
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