Synergistic inhibition of TNBC by USP33 and TAP63 through autophagy and ferroptosis activation
Abstract Background Triple-negative breast cancer (TNBC) is an aggressive malignancy lacking effective targeted therapies. Given the growing importance of regulated cell death pathways, we investigated the role of USP33 and its interaction with the tumor suppressor TAP63 in modulating ferroptosis an...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-08-01
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| Series: | Cellular and Molecular Life Sciences |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s00018-025-05833-3 |
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