Vitamin K Epoxide Reductase Complex (VKORC1) Electrochemical Genosensors: Towards the Identification of <i>1639 G>A</i> Genetic Polymorphism

Vitamin K Epoxide Reductase Complex (VKORC1) Electrochemical Genosensors: Towards the Identification of <i>1639 G>A</i> Genetic Polymorphism

Anticoagulants, including warfarin, are often administered to patients who are exhibiting early symptoms of thromboembolic episodes or who have already experienced such episodes. However, warfarin has a limited therapeutic index and might cause bleeding and other clinical problems. Warfarin inhibits...

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Main Authors: Tiago Barbosa, Stephanie L. Morais, Renato Carvalho, Júlia M. C. S. Magalhães, Valentina F. Domingues, Cristina Delerue-Matos, Hygor Ferreira-Fernandes, Giovanny R. Pinto, Marlene Santos, Maria Fátima Barroso
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Chemosensors
Subjects:
cardiovascular diseases
electrochemical genosensors
single-nucleotide polymorphisms
VKORC1
warfarin
Online Access:https://www.mdpi.com/2227-9040/13/7/248
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