Exploring the causal relationship between obesity, immune cell characteristics and cervical cancer risk using Mendelian randomization

Exploring the causal relationship between obesity, immune cell characteristics and cervical cancer risk using Mendelian randomization

Abstract Background Cervical cancer is a common malignancy among women worldwide. Obesity has been linked to numerous cancers through mechanisms involving hormonal disruption and chronic inflammation, while immune function variations may influence individual cancer susceptibility. However, the causa...

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Bibliographic Details
Main Authors: HongYin Cui, Jingjing Zhang, Xiaolin Lang, Changchang Huang, SongQing Yang
Format: Article
Language:English
Published: Springer 2025-07-01
Series:Discover Oncology
Subjects:
Mendelian randomization
Cervical cancer
Obesity
HLA expression
Regulatory T cells
Online Access:https://doi.org/10.1007/s12672-025-03111-z
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