Isobutyric Acid Promotes Immune Evasion in Colorectal Cancer via Increased PD‐L1 Expression

Isobutyric Acid Promotes Immune Evasion in Colorectal Cancer via Increased PD‐L1 Expression

ABSTRACT Introduction Isobutyric acid (IBA), a short‐chain fatty acid, has been unequivocally demonstrated to exert significant influence on the progression of colorectal cancer (CRC). Nevertheless, a comprehensive understanding of its intricate regulatory mechanisms remains elusive. Methods Employi...

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Bibliographic Details
Main Authors: Qiuhua Lin, Han Wang, Wenbo Chen, Xinjie Wei, Jinglian Chen, Ying Deng, Chunyin Wei, Hao Lai, Xianwei Mo, Weizhong Tang, Tao Luo
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Cancer Medicine
Subjects:
colorectal cancer
immune escape
isobutyric acid
PD‐L1
ROCK1
Online Access:https://doi.org/10.1002/cam4.70397
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https://doi.org/10.1002/cam4.70397

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