Antibiotic resistance among Salmonella enterica serovars Typhi and Paratyphi A in Pakistan (2001-2006)

Objectives: To compare antimicrobial resistance in S. Typhi and S. Paratyphi A isolates from Pakistan. Methods: Blood samples were collected through > 175 laboratory collection points in major cities and towns across the country. The study included 3,671 S. Typhi and 1,475 S. Paratyphi A isolates...

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Main Authors: Rumina Hasan, Afia Zafar, Zohair Abbas, Vikram Mahraj, Faisal Malik, Anita Zaidi
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2008-08-01
Series:Journal of Infection in Developing Countries
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Online Access:https://jidc.org/index.php/journal/article/view/224
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Summary:Objectives: To compare antimicrobial resistance in S. Typhi and S. Paratyphi A isolates from Pakistan. Methods: Blood samples were collected through > 175 laboratory collection points in major cities and towns across the country. The study included 3,671 S. Typhi and 1,475 S. Paratyphi A isolates (2001-2006). Multidrug resistance (MDR) was defined as resistance to first-line agents co-trimoxazole, chloramphenicol and ampicillin. Results: In total, 79.3% S. Typhi and 59.9% S. Paratyphi A were isolated from patients under 15 years of age. During the study period, the MDR rate increased in S. Typhi (34.2 to 48.5% p
ISSN:1972-2680