Cell-autonomous action of Slit2 in radial migration of cortical projection neurons

Cell-autonomous action of Slit2 in radial migration of cortical projection neurons

Neuronal radial migration is a fundamental process for cortical development, the disruption of which causes neurological and psychiatric dysfunctions. SLIT2 plays diverse functions in brain development and is a well-known axon guidance molecule. In this study, we investigated the radial migration of...

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Bibliographic Details
Main Authors: Tian Jiang, Guozhen Niu, Chunping Wu, Xiaomeng Tu, Jian Xiao, Xue Li, Jie-Guang Chen, Huateng Cao
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Molecular Neuroscience
Subjects:
SLIT2
ROBO2
radial migration
cortical development
morphogenesis
neuronal polarization
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2024.1505434/full
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https://www.frontiersin.org/articles/10.3389/fnmol.2024.1505434/full

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