Probiotic Supplementation Improves Glucose Homeostasis and Modulates Interleukin (IL)-21 and IL-22 Levels in Pediatric Patients with Type 1 Diabetes: A Randomized Placebo-Controlled Trial

Probiotic Supplementation Improves Glucose Homeostasis and Modulates Interleukin (IL)-21 and IL-22 Levels in Pediatric Patients with Type 1 Diabetes: A Randomized Placebo-Controlled Trial

<b>Background:</b> Probiotics alter gut microbiota and have beneficial effects on immune homeostasis. The role of probiotics in diabetes has been shown in some studies. Interleukin (IL)-21 and IL-22 have been implicated in the pathogenesis of type 1 diabetes mellitus (T1DM). Objectives:...

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Main Authors: Amira Abdel Moneam Adly, Eman Abdel Rahman Ismail, Mahasen Mohamed Abd-Elgawad, Nouran Yousef Salah
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Metabolites
Subjects:
probiotics
type 1 diabetes
glucose homeostasis
interleukin-21
interleukin-22
Online Access:https://www.mdpi.com/2218-1989/15/5/288
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