Tislelizumab-induced hemophagocytic lymphohistiocytosis in a patient with microsatellite instability-high colon cancer and coexisting systemic lupus erythematosus: a case report and literature review

Tislelizumab-induced hemophagocytic lymphohistiocytosis in a patient with microsatellite instability-high colon cancer and coexisting systemic lupus erythematosus: a case report and literature review

Immune checkpoint inhibitors (ICIs) have profoundly transformed the treatment landscape for microsatellite instability-high (MSI-H) colorectal cancer (CRC). However, immune-related adverse events (irAEs) remain a common and unpredictable complication among patients undergoing ICI therapy. Hemophagoc...

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Bibliographic Details
Main Authors: Pengqing Jiao, Song Wang, Jianhua Wu, Yufei Zhao, Jiaxu Han, Ziyue Sha
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Oncology
Subjects:
MSI-H
PD-1
colon cancer
SLE
HLH
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1585133/full
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