Anti-urease therapy: a targeted approach to mitigating antibiotic resistance in Helicobacter pylori while preserving the gut microflora

Anti-urease therapy: a targeted approach to mitigating antibiotic resistance in Helicobacter pylori while preserving the gut microflora

Abstract The global rise in antibiotic resistance has posed significant challenges to the effective management of Helicobacter pylori (H. pylori), a gastric pathogen linked to chronic gastritis, peptic ulcers, and gastric cancer. Conventional antibiotic therapies, while effective, face significant c...

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Bibliographic Details
Main Authors: Christina Almarmouri, Mohammed I. El-Gamal, Mohamed Haider, Mohamad Hamad, Shamsul Qumar, Merylin Sebastian, Rose Ghemrawi, Jibran Sualeh Muhammad, Christophe Burucoa, Ghalia Khoder
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Gut Pathogens
Subjects:
H. pylori
Urease
Anti-urease compounds
Antibiotic resistance
Gut microflora
Alternative antibiotic-free therapies
Online Access:https://doi.org/10.1186/s13099-025-00708-1
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