Inhibition of Neural Crest Cell Migration by Strobilurin Fungicides and Other Mitochondrial Toxicants

Inhibition of Neural Crest Cell Migration by Strobilurin Fungicides and Other Mitochondrial Toxicants

Cell-based test methods with a phenotypic readout are frequently used for toxicity screening. However, guidance on how to validate the hits and how to integrate this information with other data for purposes of risk assessment is missing. We present here such a procedure and exemplify it with a case...

Full description

Saved in:
Bibliographic Details
Main Authors: Viktoria Magel, Jonathan Blum, Xenia Dolde, Heidrun Leisner, Karin Grillberger, Hiba Khalidi, Iain Gardner, Gerhard F. Ecker, Giorgia Pallocca, Nadine Dreser, Marcel Leist
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Cells
Subjects:
neural crest cells
mitochondria
developmental toxicity
strobilurin fungicides
next-generation risk assessment
toxicokinetics
Online Access:https://www.mdpi.com/2073-4409/13/24/2057
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/2073-4409/13/24/2057

Similar Items