Internal consistency, construct validity, and responsiveness of the MRC Prion Disease Rating Scale

Abstract Background The Medical Research Council-Prion Disease Rating Scale (MRC-PDRS) is a 20-point clinician-reported outcome scale to assess disease progression in patients with prion disease, an invariably fatal neurodegenerative disease caused by misfolded prion protein. This study aims to eval...

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Bibliographic Details
Main Authors: Leah Leidy, Aaron Yarlas, Robert S. Pulido, Jessica Ludwig, Kathleen Glisic, Brian S. Appleby
Format: Article
Language:English
Published: SpringerOpen 2025-05-01
Series:Journal of Patient-Reported Outcomes
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Online Access:https://doi.org/10.1186/s41687-025-00884-3
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