POSSIBILITIY OF SHORT-TERM STRESS INFLUENCES IMPLEMENTATION IN BIOLOGICALLY ACTIVE COMPOUNDS SCREENING

POSSIBILITIY OF SHORT-TERM STRESS INFLUENCES IMPLEMENTATION IN BIOLOGICALLY ACTIVE COMPOUNDS SCREENING

This work presents the analysis of phobic anxiety behavioral reactions connected with short-term stress influences. We have established that 15 minutes forced swimming reduces locomotory and exploratory activity of animals without any connection with physical exhaustion. Short-term isolation provoke...

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Bibliographic Details
Main Authors: A. S. Tarasov, E. I. Morkovin, V. V. Stepanova
Format: Article
Language:Russian
Published: Volgograd State Medical University, Pyatigorsk Medical and Pharmaceutical Institute 2015-09-01
Series:Фармация и фармакология (Пятигорск)
Subjects:
stress
anxiety
forced swimming
isolation
immobilization
pre-clinical studies methods.
Online Access:https://www.pharmpharm.ru/jour/article/view/130
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Summary:This work presents the analysis of phobic anxiety behavioral reactions connected with short-term stress influences. We have established that 15 minutes forced swimming reduces locomotory and exploratory activity of animals without any connection with physical exhaustion. Short-term isolation provokes the increase of irrational searching activity connected with spatial disorder and agitation. During this work we have formed an algorithm which allowed fast screening of anxio-lytics and antidepressants
ISSN:2307-9266
2413-2241

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