Machine learning-based plasma metabolomics for improved cirrhosis risk stratification

Machine learning-based plasma metabolomics for improved cirrhosis risk stratification

Abstract Background Cirrhosis is a leading cause of mortality in patients with chronic liver disease (CLD). The rapid development of metabolomic technologies has enabled the capture of metabolic changes related to the progression of cirrhosis. Methods This study used proton nuclear magnetic resonanc...

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Bibliographic Details
Main Authors: Jingru Song, Ziwei Gao, Liqun Lai, Jie Zhang, Binbin Liu, Yi Sang, Siqi Chen, Jiachen Qi, Yujun Zhang, Huang Kai, Wei Ye
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Gastroenterology
Subjects:
Cirrhosis
Chronic liver disease
Metabolomics
Risk stratification
Elastic net regularization
Online Access:https://doi.org/10.1186/s12876-025-03655-y
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