Molecular hydrogen mitigates traumatic brain injury-induced lung injury via NLRP3 inflammasome inhibition

Molecular hydrogen mitigates traumatic brain injury-induced lung injury via NLRP3 inflammasome inhibition

Abstract Introduction Hydrogen gas has demonstrated significant antioxidant and anti-inflammatory properties, suggesting potential therapeutic benefits in TBI. Methods We subjected to controlled cortical impact in mice to construct TBI model. They received an intraperitoneal injection of MCC950, a s...

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Bibliographic Details
Main Authors: Lingling Liu, Shuzhi Wang, Lianhao Jiang, Jiwei Wang, Jun Chen, Hongtao Zhang, Yuanlin Wang
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Chemistry
Subjects:
Hydrogen gas
Traumatic brain injury
Lung injury
NLRP3 inflammasome
Online Access:https://doi.org/10.1186/s13065-025-01513-2
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