Understanding the development of tuberculous granulomas: insights into host protection and pathogenesis, a review in humans and animals

Understanding the development of tuberculous granulomas: insights into host protection and pathogenesis, a review in humans and animals

Granulomas, organized aggregates of immune cells which form in response to Mycobacterium tuberculosis (Mtb), are characteristic but not exclusive of tuberculosis (TB). Despite existing investigations on TB granulomas, the determinants that differentiate host-protective granulomas from granulomas tha...

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Bibliographic Details
Main Authors: Jiwon Lyu, Drew E. Narum, Susan L. Baldwin, Sasha E. Larsen, Xiyuan Bai, David E. Griffith, Véronique Dartois, Threnesan Naidoo, Adrie J. C. Steyn, Rhea N. Coler, Edward D. Chan
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Immunology
Subjects:
tuberculosis
pathology
animal models
immunology
lung
mycobacteria
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1427559/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1427559/full

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