DNA tetrahedron nanoparticles service as a help carrier and adjvant of mRNA vaccine

Abstract Aim of the study To investigate the potential of DNA nanoparticles (DNPs) as carriers and adjuvants for mRNA vaccines. Materials and methods Customized oligonucleotides were assembled into DNA tetrahedra (DNA-TH), which were subsequently complexed with streptavidin and mRNA encoding green f...

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Bibliographic Details
Main Authors: Henglang Liu, Xianxian Li, Ruike Yan, Jing Yang, Qun Lu, Lili Wang
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-024-05837-w
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