Natural killer cells occupy unique spatial neighborhoods in HER2- and HER2+ human breast cancers
Abstract Tumor-infiltrating lymphocytes are considered clinically beneficial in breast cancer, but the significance of natural killer (NK) cells is less well characterized. As increasing evidence has demonstrated that the spatial organization of immune cells in tumor microenvironments is a significa...
Saved in:
Main Authors: | Femke A. I. Ehlers, Katie E. Blise, Courtney B. Betts, Shamilene Sivagnanam, Loes F. S. Kooreman, E. Shelley Hwang, Gerard M. J. Bos, Lotte Wieten, Lisa M. Coussens |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2025-01-01
|
Series: | Breast Cancer Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13058-025-01964-4 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Targeting of the HER2/HER3 signaling axis overcomes ligand‐mediated resistance to trastuzumab in HER2‐positive breast cancer
by: Satomi Watanabe, et al.
Published: (2019-03-01) -
<i>shp-2</i> gene knockout upregulates CAR-driven cytotoxicity of YT NK cells
by: V. G. Subrakova, et al.
Published: (2020-03-01) -
Subtype-specific prognostic impact of Bcl-2 in HER2-positive and HER2-negative breast cancer
by: Taeyeong Kim, et al.
Published: (2025-01-01) -
Natural killer cell engagers for cancer immunotherapy
by: Shahryar Khoshtinat Nikkhoi, et al.
Published: (2025-01-01) -
Identification of m6A methyltransferase-related WTAP and ZC3H13 predicts immune infiltrates in glioblastoma
by: Liyun Gao, et al.
Published: (2025-02-01)