Liposomal and Nanostructured Lipid Nanoformulations of a Pentacyclic Triterpenoid Birch Bark Extract: Structural Characterization and In Vitro Effects on Melanoma B16-F10 and Walker 256 Tumor Cells Apoptosis

Liposomal and Nanostructured Lipid Nanoformulations of a Pentacyclic Triterpenoid Birch Bark Extract: Structural Characterization and In Vitro Effects on Melanoma B16-F10 and Walker 256 Tumor Cells Apoptosis

<b>Background/Objectives</b>: Pentacyclic triterpenoids are increasingly studied as anticancer agents with many advantages compared to synthetic chemotherapeutics. The aim of this study was to prepare liposomal and nanostructured lipid formulations including a standardized extract of sil...

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Bibliographic Details
Main Authors: Dumitriţa Rugină, Mihai Adrian Socaciu, Madalina Nistor, Zorita Diaconeasa, Mihai Cenariu, Flaviu Alexandru Tabaran, Carmen Socaciu
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Pharmaceuticals
Subjects:
pentacyclic triterpenoids
PEGylated liposomes
nanolipid complexes
diffraction light scattering
melanoma B16-F10 and walker 256 carcinoma cells
cell cycle arrest
Online Access:https://www.mdpi.com/1424-8247/17/12/1630
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