Comparison of the CHU-9D and the EQ-5D-Y instruments in children and young people with cerebral palsy: a cross-sectional study
Objective To compare the performance of the EuroQol 5D youth (EQ-5D-Y) and child health utility 9D (CHU-9D) for assessing health-related quality of life (HRQoL) in children and young people (CYP) with cerebral palsy (CP).Design Cross-sectional study.Setting England.Participants Sixty-four CYP with C...
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BMJ Publishing Group
2020-09-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/10/9/e037089.full |
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| author | Jennifer M Ryan Nana Anokye Grace Lavelle Ellen McKay Marika Noorkoiv Nicola Theis |
| author_facet | Jennifer M Ryan Nana Anokye Grace Lavelle Ellen McKay Marika Noorkoiv Nicola Theis |
| author_sort | Jennifer M Ryan |
| collection | DOAJ |
| description | Objective To compare the performance of the EuroQol 5D youth (EQ-5D-Y) and child health utility 9D (CHU-9D) for assessing health-related quality of life (HRQoL) in children and young people (CYP) with cerebral palsy (CP).Design Cross-sectional study.Setting England.Participants Sixty-four CYP with CP aged 10–19 years in Gross Motor Function Classification System (GMFCS) levels I–III.Main outcome measures Missing data were examined to assess feasibility. Associations between utility values and individual dimensions on each instrument were examined to assess convergent validity. Associations between utility values and GMFCS level were examined to assess known-group differences.Results Missing data were <5% for both instruments. Twenty participants (32.3%) and 11 participants (18.0%) reported full health for the EQ-5D-Y and CHU-9D, respectively. There was poor agreement between utilities from the two instruments (intraclass correlation coefficient=0.62; 95% limits of agreement −0.58 to 0.29). Correlations between EQ-5D-Y and CHU-9D dimensions were weak to moderate (r=0.25 to 0.59). GMFCS level was associated with EQ-5D-Y utility values but not CHU-9D utility values.Conclusion The EQ-5D-Y and CHU-9D are feasible measures of HRQoL in CYP with CP. However, the two instruments demonstrate poor agreement and should not be used to measure and value HRQoL in CYP with CP interchangeably. We propose that the CHU-9D may be preferable to use in this population as it assesses concepts that influence HRQoL among CYP with CP and provides less extreme utility values than the EQ-5D-Y. |
| format | Article |
| id | doaj-art-f29fff04d07449a7878cb243ed34d415 |
| institution | Kabale University |
| issn | 2044-6055 |
| language | English |
| publishDate | 2020-09-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-f29fff04d07449a7878cb243ed34d4152025-01-08T06:20:13ZengBMJ Publishing GroupBMJ Open2044-60552020-09-0110910.1136/bmjopen-2020-037089Comparison of the CHU-9D and the EQ-5D-Y instruments in children and young people with cerebral palsy: a cross-sectional studyJennifer M Ryan0Nana Anokye1Grace Lavelle2Ellen McKay3Marika Noorkoiv4Nicola Theis5Department of Public Health and Epidemiology, RCSI University of Medicine and Health Sciences, Dublin, Ireland1 Health Economics Research Group, Department of Clinical Sciences, College of Health and Life Sciences, Brunel University London, Uxbridge, UKDepartment of Psychological Medicine, Institute of Psychology, Psychiatry and Neuroscience, King’s College London, London, UKDepartment of Public Health and Epidemiology, Royal College of Surgeons in Ireland, Dublin, IrelandCollege of Health, Medicine and Life Sciences, Brunel University London, Uxbridge, Middlesex, UKSchool of Sport and Exercise, University of Gloucestershire, Cheltenham, Gloucestershire, UKObjective To compare the performance of the EuroQol 5D youth (EQ-5D-Y) and child health utility 9D (CHU-9D) for assessing health-related quality of life (HRQoL) in children and young people (CYP) with cerebral palsy (CP).Design Cross-sectional study.Setting England.Participants Sixty-four CYP with CP aged 10–19 years in Gross Motor Function Classification System (GMFCS) levels I–III.Main outcome measures Missing data were examined to assess feasibility. Associations between utility values and individual dimensions on each instrument were examined to assess convergent validity. Associations between utility values and GMFCS level were examined to assess known-group differences.Results Missing data were <5% for both instruments. Twenty participants (32.3%) and 11 participants (18.0%) reported full health for the EQ-5D-Y and CHU-9D, respectively. There was poor agreement between utilities from the two instruments (intraclass correlation coefficient=0.62; 95% limits of agreement −0.58 to 0.29). Correlations between EQ-5D-Y and CHU-9D dimensions were weak to moderate (r=0.25 to 0.59). GMFCS level was associated with EQ-5D-Y utility values but not CHU-9D utility values.Conclusion The EQ-5D-Y and CHU-9D are feasible measures of HRQoL in CYP with CP. However, the two instruments demonstrate poor agreement and should not be used to measure and value HRQoL in CYP with CP interchangeably. We propose that the CHU-9D may be preferable to use in this population as it assesses concepts that influence HRQoL among CYP with CP and provides less extreme utility values than the EQ-5D-Y.https://bmjopen.bmj.com/content/10/9/e037089.full |
| spellingShingle | Jennifer M Ryan Nana Anokye Grace Lavelle Ellen McKay Marika Noorkoiv Nicola Theis Comparison of the CHU-9D and the EQ-5D-Y instruments in children and young people with cerebral palsy: a cross-sectional study BMJ Open |
| title | Comparison of the CHU-9D and the EQ-5D-Y instruments in children and young people with cerebral palsy: a cross-sectional study |
| title_full | Comparison of the CHU-9D and the EQ-5D-Y instruments in children and young people with cerebral palsy: a cross-sectional study |
| title_fullStr | Comparison of the CHU-9D and the EQ-5D-Y instruments in children and young people with cerebral palsy: a cross-sectional study |
| title_full_unstemmed | Comparison of the CHU-9D and the EQ-5D-Y instruments in children and young people with cerebral palsy: a cross-sectional study |
| title_short | Comparison of the CHU-9D and the EQ-5D-Y instruments in children and young people with cerebral palsy: a cross-sectional study |
| title_sort | comparison of the chu 9d and the eq 5d y instruments in children and young people with cerebral palsy a cross sectional study |
| url | https://bmjopen.bmj.com/content/10/9/e037089.full |
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