Ablation of IGFBP5 expression alleviates neurogenic erectile dysfunction by inducing neurovascular regeneration

Ablation of IGFBP5 expression alleviates neurogenic erectile dysfunction by inducing neurovascular regeneration

"Purpose: To investigate the therapeutic potential of eliminating insulin-like growth factor-binding protein 5 (IGFBP5) expression in improving erectile function in mice with cavernous nerve injury (CNI)-induced erectile dysfunction (ED). Materials and Methods: Eight-week-old male C57BL/6 mice...

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Bibliographic Details
Main Authors: Jiyeon Ock, Guo Nan Yin, Fang-Yuan Liu, Yan Huang, Fitri Rahma Fridayana, Minh Nhat Vo, Ji-Kan Ryu
Format: Article
Language:English
Published: Korean Urological Association 2025-01-01
Series:Investigative and Clinical Urology
Subjects:
apoptosis
erectile dysfunction
insulin-like growth factor binding protein 5
nerve regeneration
reactive oxygen species
Online Access:https://www.icurology.org/pdf/10.4111/icu.20240325
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https://www.icurology.org/pdf/10.4111/icu.20240325

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