SDF-1α loaded lipid liquid crystalline hydrogel accelerates diabetic wound healing in in vitro and in vivo models

SDF-1α loaded lipid liquid crystalline hydrogel accelerates diabetic wound healing in in vitro and in vivo models

Abstract Diabetes mellitus (DM) significantly impairs wound healing, often leading to chronic wounds with limited effective treatment options. Existing treatments often fail to provide sustained therapeutic effects, underscoring the need for advanced biomaterial-based approaches to enhance tissue re...

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Bibliographic Details
Main Authors: Farzad Sadri, Zohreh Rezaei, Hossein Safarpour, Hossein Kamali, Mehri Shadi, Pouria Mohammadparast-Tabas, Mohammad Fereidouni
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
SDF-1α
Lipid liquid crystalline hydrogel
Diabetic wound healing
Fibroblast migration
Tissue regeneration
STZ-diabetic model
Online Access:https://doi.org/10.1038/s41598-025-10756-x
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https://doi.org/10.1038/s41598-025-10756-x

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