Nucleotide-binding oligomerization domain 1 (NOD1) regulates microglial activation in pseudorabies virus infection

Nucleotide-binding oligomerization domain 1 (NOD1) regulates microglial activation in pseudorabies virus infection

Abstract The primary cause of viral encephalitis (VE) is invasion of the central nervous system (CNS) by the virus, which leads to neuroinflammation and poses a significant threat to global public health. Microglia, as CNS-resident macrophages, play a crucial role in neuroinflammation and are often...

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Bibliographic Details
Main Authors: Xiuxiu Sun, Xinxin Jin, Zhengdan Lin, Xi Liu, Junjie Yang, Li Li, Helong Feng, Wanpo Zhang, Changqin Gu, Xueying Hu, Xiaoli Liu, Guofu Cheng
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Veterinary Research
Subjects:
Microglia
neuroinflammation
pseudorabies virus
NOD1
JNK
NF-κB
Online Access:https://doi.org/10.1186/s13567-024-01416-5
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https://doi.org/10.1186/s13567-024-01416-5

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