Differentiation‐related epigenomic changes define clinically distinct keratinocyte cancer subclasses

Differentiation‐related epigenomic changes define clinically distinct keratinocyte cancer subclasses

Abstract Keratinocyte cancers (KC) are the most prevalent malignancies in fair‐skinned populations, posing a significant medical and economic burden to health systems. KC originate in the epidermis and mainly comprise basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (cSCC). Here, we...

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Main Authors: Llorenç Solé‐Boldo, Günter Raddatz, Julian Gutekunst, Oliver Gilliam, Felix Bormann, Michelle S Liberio, Daniel Hasche, Wiebke Antonopoulos, Jan‐Philipp Mallm, Anke S Lonsdorf, Manuel Rodríguez‐Paredes, Frank Lyko
Format: Article
Language:English
Published: Springer Nature 2022-09-01
Series:Molecular Systems Biology
Subjects:
cell‐of‐origin
epigenetics
keratinocyte cancers
single‐cell
Online Access:https://doi.org/10.15252/msb.202211073
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