Neuronal Plasticity-Dependent Paradigm and Young Plasma Treatment Prevent Synaptic and Motor Deficit in a Rett Syndrome Mouse Model

Classical Rett syndrome (RTT) is a neurodevelopmental disorder caused by mutations in the <i>MECP2</i> gene, resulting in a devastating phenotype associated with a lack of gene expression control. Mouse models lacking <i>Mecp2</i> expression with an RTT-like phenotype have be...

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Main Authors:	Sofía Espinoza, Camila Navia, Rodrigo F. Torres, Nuria Llontop, Verónica Valladares, Cristina Silva, Ariel Vivero, Exequiel Novoa-Padilla, Jessica Soto-Covasich, Jessica Mella, Ricardo Kouro, Sharin Valdivia, Marco Pérez-Bustamante, Patricia Ojeda-Provoste, Nancy Pineda, Sonja Buvinic, Dasfne Lee-Liu, Juan Pablo Henríquez, Bredford Kerr
Format:	Article
Language:	English
Published:	MDPI AG 2025-05-01
Series:	Biomolecules
Subjects:	Rett syndrome <i>Mecp2</i> environmental enrichment plasma treatment
Online Access:	https://www.mdpi.com/2218-273X/15/5/748
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Neuronal Plasticity-Dependent Paradigm and Young Plasma Treatment Prevent Synaptic and Motor Deficit in a Rett Syndrome Mouse Model

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