Extracellular matrix dynamics in tumor immunoregulation: from tumor microenvironment to immunotherapy

Abstract The extracellular matrix (ECM), closely linked to the dynamic changes in the tumor microenvironment (TME), plays a critical role in modulating tumor immunity. The dual role of the ECM in tumor progression, encompassing both promotion and inhibition, is attributed to its components influenci...

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Bibliographic Details
Main Authors: Qin Hu, Yifei Zhu, Jie Mei, Ying Liu, Guoren Zhou
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Journal of Hematology & Oncology
Online Access:https://doi.org/10.1186/s13045-025-01717-y
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