Single cell RNA-sequencing of feline peripheral immune cells with V(D)J repertoire and cross species analysis of T lymphocytes

Single cell RNA-sequencing of feline peripheral immune cells with V(D)J repertoire and cross species analysis of T lymphocytes

IntroductionThe domestic cat (Felis catus) is a valued companion animal and a model for virally induced cancers and immunodeficiencies. However, species-specific limitations such as a scarcity of immune cell markers constrain our ability to resolve immune cell subsets at sufficient detail. The goal...

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Bibliographic Details
Main Authors: Raneesh Ramarapu, Judit M. Wulcan, Haiyang Chang, Peter F. Moore, William Vernau, Stefan M. Keller
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Immunology
Subjects:
feline
T cells
single cell RNA-sequencing (scRNA-seq)
T-cell receptor repertoire
cross species analysis
myeloid Cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1438004/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1438004/full

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