Plasmonic Molecular Entrapment for Label‐Free Methylated DNA Detection and Machine‐Learning Assisted Quantification

Plasmonic Molecular Entrapment for Label‐Free Methylated DNA Detection and Machine‐Learning Assisted Quantification

Abstract Epigenetic DNA methylations are linked to the activation of oncogenes and inactivation of tumor suppressor genes. A reliable and label‐free method to quantitatively measure DNA methylation levels is essential for diagnosing and monitoring methylation‐related diseases. Herein, plasmonic mole...

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Main Authors: Muhammad Shalahuddin Al Ja'farawy, Vo Thi Nhat Linh, Chaewon Mun, Jun‐Yeong Yang, Jun Young Kim, Rowoon Park, Sung‐Gyu Park, Dong‐Ho Kim, Min‐Young Lee, Ho Sang Jung
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:Advanced Science
Subjects:
DNA methylation
hotspot engineering
label‐free diagnosis
plasmonic materials
surface‐enhanced Raman scattering
Online Access:https://doi.org/10.1002/advs.202503257
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https://doi.org/10.1002/advs.202503257

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