In-vivo real-time control of protein expression from endogenous and synthetic gene networks.

We describe an innovative experimental and computational approach to control the expression of a protein in a population of yeast cells. We designed a simple control algorithm to automatically regulate the administration of inducer molecules to the cells by comparing the actual protein expression le...

Full description

Saved in:
Bibliographic Details
Main Authors: Filippo Menolascina, Gianfranco Fiore, Emanuele Orabona, Luca De Stefano, Mike Ferry, Jeff Hasty, Mario di Bernardo, Diego di Bernardo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-05-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1003625
Tags: Add Tag
No Tags, Be the first to tag this record!