Nuclear N-WASP Induces Actin Polymerization in the Nucleus with Cortactin as an Essential Factor
Nuclear actin polymerization was reported to control different nuclear processes, but its regulation is poorly understood. Here, we show that N-WASP can trigger the formation of nuclear N-WASP/F-actin nodules. While a cancer hotspot mutant of N-WASP lacking the VCA domain (V418fs) had a dominant neg...
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Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2025-01-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/14/1/59 |
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