Light Hygiene for Circadian Health: A Molecular Perspective

In discussing the interplay between light exposure/blue light exposure (LE/BLE) and circadian health, we emphasize the role of light hygiene and its effects on maintaining sleep, mood, and metabolic health, among other physiological processes. We define compromised circadian light hygiene as low dyn...

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Main Authors: Denis Gubin, Oliver Stefani, Germaine Cornelissen
Format: Article
Language:English
Published: IMR Press 2025-07-01
Series:Frontiers in Bioscience-Landmark
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Online Access:https://www.imrpress.com/journal/FBL/30/7/10.31083/FBL39097
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author Denis Gubin
Oliver Stefani
Germaine Cornelissen
author_facet Denis Gubin
Oliver Stefani
Germaine Cornelissen
author_sort Denis Gubin
collection DOAJ
description In discussing the interplay between light exposure/blue light exposure (LE/BLE) and circadian health, we emphasize the role of light hygiene and its effects on maintaining sleep, mood, and metabolic health, among other physiological processes. We define compromised circadian light hygiene as low dynamic range and/or irregular 24-hour patterns of LE. Poor light hygiene interferes with circadian entrainment and weakens circadian robustness alignment, thereby increasing health hazards. We provide an overview of the complex molecular pathways underlying light perception and downstream signaling. Given that genetic polymorphisms influence key elements within these light signaling pathways, we propose that personalized light hygiene approaches be designed for populations affected by compromised circadian LE or at risk of light-induced circadian disruption.
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series Frontiers in Bioscience-Landmark
spelling doaj-art-f022b58d90b340eb9afcaa1e36ce3ec62025-08-20T03:44:35ZengIMR PressFrontiers in Bioscience-Landmark2768-67012025-07-013073909710.31083/FBL39097S2768-6701(25)01768-XLight Hygiene for Circadian Health: A Molecular PerspectiveDenis Gubin0Oliver Stefani1Germaine Cornelissen2Department of Biology, Tyumen Medical University, 625023 Tyumen, RussiaDepartment Engineering and Architecture, Institute of Building Technology and Energy, Lucerne University of Applied Sciences and Arts, 6048 Horw, SwitzerlandHalberg Chronobiology Center, University of Minnesota, Minneapolis, MN 55455, USAIn discussing the interplay between light exposure/blue light exposure (LE/BLE) and circadian health, we emphasize the role of light hygiene and its effects on maintaining sleep, mood, and metabolic health, among other physiological processes. We define compromised circadian light hygiene as low dynamic range and/or irregular 24-hour patterns of LE. Poor light hygiene interferes with circadian entrainment and weakens circadian robustness alignment, thereby increasing health hazards. We provide an overview of the complex molecular pathways underlying light perception and downstream signaling. Given that genetic polymorphisms influence key elements within these light signaling pathways, we propose that personalized light hygiene approaches be designed for populations affected by compromised circadian LE or at risk of light-induced circadian disruption.https://www.imrpress.com/journal/FBL/30/7/10.31083/FBL39097circadianlightlight hygienemelatoninmoodmetabolism
spellingShingle Denis Gubin
Oliver Stefani
Germaine Cornelissen
Light Hygiene for Circadian Health: A Molecular Perspective
Frontiers in Bioscience-Landmark
circadian
light
light hygiene
melatonin
mood
metabolism
title Light Hygiene for Circadian Health: A Molecular Perspective
title_full Light Hygiene for Circadian Health: A Molecular Perspective
title_fullStr Light Hygiene for Circadian Health: A Molecular Perspective
title_full_unstemmed Light Hygiene for Circadian Health: A Molecular Perspective
title_short Light Hygiene for Circadian Health: A Molecular Perspective
title_sort light hygiene for circadian health a molecular perspective
topic circadian
light
light hygiene
melatonin
mood
metabolism
url https://www.imrpress.com/journal/FBL/30/7/10.31083/FBL39097
work_keys_str_mv AT denisgubin lighthygieneforcircadianhealthamolecularperspective
AT oliverstefani lighthygieneforcircadianhealthamolecularperspective
AT germainecornelissen lighthygieneforcircadianhealthamolecularperspective