Efficient Synthesis of Novel Triazolo[5,1-<i>b</i>]purines by Diacetoxyiodobenzene-Mediated Oxidative Cyclization of Schiff Bases

Efficient Synthesis of Novel Triazolo[5,1-<i>b</i>]purines by Diacetoxyiodobenzene-Mediated Oxidative Cyclization of Schiff Bases

In this work, we have developed a method for synthesizing new 8-substituted triazolo[5,1-<i>b</i>]purines using diacetoxyiodobenzene as an oxidizing agent with good yields (59–67%). The advantages of this approach include mild reaction conditions and removing the need to use transition m...

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Bibliographic Details
Main Authors: Artyom O. Neymash, Victor V. Fedotov, Evgeny N. Ulomsky, Daniil N. Lyapustin, Semen V. Aminov, Vladimir L. Rusinov
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Reactions
Subjects:
purines
pyrimidine
oxidation
triazolo[5,1-<i>b</i>]purines
cyclization
azolo[1,5-<i>a</i>]pyrimidines
Online Access:https://www.mdpi.com/2624-781X/5/4/58
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