Long-term survival of a SMARCA4-deficient undifferentiated thoracic tumor with brain metastasis successfully treated with multimodal treatment: a case report and literature review

Abstract Background SMARCA4-deficient undifferentiated thoracic tumor (SMARCA4-UT) is a rare and highly aggressive malignancy characterized by early distant metastasis and a poor prognosis, with a median overall survival (OS) of only 4–7 months. Traditional therapies offer limited benefit, while eme...

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Bibliographic Details
Main Authors: Yu Gan, Qi Hu, Fangfang Hu, Shugui Wu
Format: Article
Language:English
Published: Springer 2025-08-01
Series:Journal of Cancer Research and Clinical Oncology
Subjects:
Online Access:https://doi.org/10.1007/s00432-025-06284-w
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